发明名称 LIPIDS IN THE AQUEOUS PHASE
摘要 The present invention relates to a novel advantageous process for the preparation of unilamellar liposomes in aqueous phase by converting a suitable lipid component, e.g. phosphatidic acid, into the ionic form by subjecting the lipid dispersion to a change in pH value and subsequently neutralizing it. Formation of the unilamellar liposomes is spontaneous, i.e. it takes place without additional external supply of energy. The liposomes obtainable by the process of this invention can be used therapeutically as carriers for drugs of the most widely different kind.
申请公布号 EP0088046(A3) 申请公布日期 1984.02.08
申请号 EP19830810060 申请日期 1983.02.11
申请人 CIBA-GEIGY AG 发明人 HAUSER, HELMUT, DR.
分类号 A61K9/127;A61K9/133;(IPC1-7):61K9/50 主分类号 A61K9/127
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