AMINO-DIOXEPANE INTERMEDIATES FOR THE SYNTHESIS OF NEW NON-IONIC CONTRAST MEDIA

摘要

Novel intermediates for non ionic polyiodo amino-substituted benzenepolyamides having polyol substituents on the amide nitrogens are provided which are 5-amino-6-hydroxy-1,3-dioxepanes. The compounds provide an economic and efficient route to novel contrast media having excellent chemical and physiological properties. Also provided are methods for preparing the subject compounds.