发明名称 SALT OF FUROSEMIDE OR PIRETANIDE AS THE ACID COMPONENT AND PENBUTOLOL OR (-)-3-[4-[3-(3,4-DIMETHOXYPHENY LETHYLAMINO)-2-HYDROXYPROPOXY]-PHENYL]-CROTONONI- TRILE AS THE BASE COMPONENT, PROCESS FOR ITS PREPARA- TION, COMPOSITON IN WHICH IT IS PRESENT AND ITS USE
摘要 <p>Salt of furosemide or piretanide as the acid component and penbutolol or (-)-3-¢4-¢3-(3.4-dimethoxyphenylethyl-amino)-2-hydroxypropoxy!-phenyl!-crotononitrile as the base component. process for its preparation. composition in which it is present and its use The subject of the invention is a salt of furosemide or piretanide as the acid component and penbutolol or (-)-3-¢4-¢3-¢3.4-dimethoxyphenylethylamino)-2-hydroxy-propoxy!-phenyl!-crotononitrile as the base component, and a process for its preparation, and also a composition containing at least two of the following components: (A) furosemide or piretanide. (B) penbutolol or (-)-3-¢4-¢3-(3.4-dimethoxy-phenylethylemino)-2-hydroxypropoxy!-phenyl,!-crotononitrile, and (C) the abovementioned salt, and the use of this composition for the treatment of diseases of the coronary and circulatory system.</p>
申请公布号 CA1161449(A) 申请公布日期 1984.01.31
申请号 CA19810381058 申请日期 1981.07.03
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 MUSCHAWECK, ROMAN;FUELBERTH, WERNER;SICKMUELLER, ALFRED
分类号 C07D295/14;A61K31/13;A61K31/275;A61K31/34;A61K31/341;A61K31/40;A61K31/402;A61K31/635;A61P9/12;C07D295/08;C07D295/155;C07D307/52;(IPC1-7):C07D207/09;C07D307/54 主分类号 C07D295/14
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