发明名称 PREPARATION OF NONFLOCCULATING MICROCAPSULE
摘要 PURPOSE:To obtain mononuclear microcapsules, having a core material coated with dense and uniform wall membranes, and rich in fluidity, by separating phases from a cyclohexane solution containing ethyl cellulose with a specific hydrocarbon compound as a phase separation inducing agent. CONSTITUTION:0.1-20vol% hydrocarbon compound, having 7-10 (cal/cm<3>)<1/2> solubility parameter (delta) and 150-3,000 molecular weight, and soluble in cyclohexane, e.g. liquid paraffin, vaseline, squalane, polybutadiene or polystyrene, as a phase separation inducing agent is added to a solution containing 0.5- 10wt% ethyl cellulose in the cyclohexane, stirring the resultant mixture under heating to prepare a dispersion of the core material, and the resultant dispersion is then cooled under stirring to give the aimed microcapsules.
申请公布号 JPS5916821(A) 申请公布日期 1984.01.28
申请号 JP19820124829 申请日期 1982.07.16
申请人 TANABE SEIYAKU KK 发明人 SAMEJIMA MASAYOSHI;HIRATA GOICHI;ISHIBASHI TAKASHI
分类号 A61K9/62;A61K9/50;B01J13/02;B01J13/08;B01J13/12 主分类号 A61K9/62
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