发明名称 |
OPTICALLY ACTIVE 1-AROMATIC-GROUP-SUBSTITUTED-1-ALKANONES AND METHODS FOR THEIR MANUFACTURE |
摘要 |
A manufacturing method is described for the preparation of optically active 1-aromatic-group-substituted-1-alkanones characterized in that an optically active alkane acid halide is allowed to react with an aromatic compound in the presence of a Lewis acid. The optically active 1-aromatic-group-substituted-1-alkanones are useful intermediates in the preparation of optically active alpha-arylalkanoic acids, which are useful as pharmaceutical, e.g. anti-inflammatory, analgesic and anti-pyretic, agents and as insecticidal agents. |
申请公布号 |
ZA8204179(B) |
申请公布日期 |
1984.01.25 |
申请号 |
ZA19820004179 |
申请日期 |
1982.06.14 |
申请人 |
SYNTEX PHARMACEUTICALS INTERNATIONAL LTD |
发明人 |
GEN-ICHI TSUCHIHASHI;SHUICHI MITAMURA;KOJI KITAJIMA |
分类号 |
C07C45/68;B01J27/125;B01J27/128;C07B31/00;C07B41/06;C07B53/00;C07B61/00;C07C43/315;C07C45/00;C07C45/46;C07C49/76;C07C49/80;C07C49/82;C07C49/84;C07C57/30;C07C67/00;C07C69/612;C07C301/00;C07C303/30;C07C309/63;C07C309/66;C07C309/73 |
主分类号 |
C07C45/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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