发明名称 |
Antimicrobial disulfide prodrugs |
摘要 |
A series of prodrugs is described which have improved antimicrobial activity and physico-chemical properties. The structures of the biologically active ingredients are characterized by having a selected oligopeptide backbone attached, via the alpha -carbon of an L-alanyl unit thereof, by means of a disulfide link to the residue of an antimicrobial mercaptan.
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申请公布号 |
US4427582(A) |
申请公布日期 |
1984.01.24 |
申请号 |
US19820386365 |
申请日期 |
1982.06.08 |
申请人 |
SMITHKLINE BECKMAN CORPORATION |
发明人 |
GILVARG, CHARLES;KINGSBURY, WILLIAM D. |
分类号 |
A01N41/12;A01N43/40;A61K38/00;A61P31/04;A61P31/10;C07D213/70;C07D213/89;C07K5/02;C07K5/04;C07K5/06;C07K5/068;C07K7/06;(IPC1-7):C07C103/52;A61K37/00 |
主分类号 |
A01N41/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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