| 摘要 |
<p>x-4771-(A) Dimeric indole-dihydroindole compounds of the formula I wherein R is OCH3, NH2, NHCH3, NHC2H5, NHC2H4OH or NH-NH2; R1 is OH or acetoxy; R2 is CH3 or CHO; and R4 is NH-C-R wherein R is H, methyl, NHCOO methy! or methylthliomethyl; and their Pharmaceutically-acceptable acid addition salts, active as anti-tumor agents in mammals, are prepared from their C-4' hydroxy analogues by reaction with hydrogen cyanide or nitriles under strongly acidic conditions.</p> |
