发明名称 AZABICYCLOALKYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 A compound of the formula (I), and pharmaceutically acceptable salts thereof: <CHEM> wherein: R1 is a C1-6 alkoxy group; R2 and R3 are the same or different and are hydrogen, halogen, CF3, C2-7 acyl, C2-7 acylamino, or amino, aminocarbonyl or aminosulphone optionally substituted by one or two C1-6 alkyl groups, C1-6 alkylsulphone or nitro; R5 is hydrogen or C1-6 alkyl; R6 is C1-7 alkyl or a group -(CH2)sR7 where s is 0 to 2 and R7 is a C3-8 cycloalkyl group, or a group -(CH2)tRs where t is 1 or 2 and Rs is C2-5 alkenyl or a phenyl group optionally substituted by one or two substituents selected from C1-6 alkyl, C1-4 alkoxy, trifluoromethyl and halogen; and n, p and q are independently 0 to 2; have useful pharmacological activity.
申请公布号 DE2966476(D1) 申请公布日期 1984.01.12
申请号 DE19792966476 申请日期 1979.12.20
申请人 BEECHAM GROUP PLC 发明人 HADLEY, MICHAEL STEWART;KING, FRANCIS DAVID
分类号 C07D451/02;C07D451/04;C07D451/14;C07D471/08;C07D487/08;(IPC1-7):07D451/04;07D487/08;07D451/14;07D451/02;61K31/395 主分类号 C07D451/02
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