发明名称 New and novel glycosides, glycoconjugates and processes for their preparation.
摘要 <p>An O-glycoside having the general formula: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="4" wi="33" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein Hal is chlorine, bromine or iodine, m is an integer of 2-20 inclusive and n is an integer of 1 to 10, inclusive, with the proviso that when n = 1 and m = 2, the aldose is different from glucose;</p><p>An O-glycoside having the general formula: &lt;Chemistry id="chema02" num="0002"&gt;&lt;Image id="ia02" he="4" wi="40" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein n is an integer of from 1-10, inclusive, m is an integer of from 2-20, inclusive, R is selected from the group consisting of alkyl having at most 25 carbon atoms and aryl and R' is selected from the group consisting of H, CHO, CH(OR")&lt;Sub&gt;2&lt;/Sub&gt;, NO2, NH&lt;Sub&gt;2&lt;/Sub&gt;, OH, SH, COOH, COOCH&lt;Sub&gt;3&lt;/Sub&gt;, COOCH&lt;Sub&gt;2&lt;/Sub&gt;CH&lt;Sub&gt;3&lt;/Sub&gt;, CONHNH&lt;Sub&gt;2&lt;/Sub&gt; and CON&lt;Sub&gt;3&lt;/Sub&gt;, wherein R" is C&lt;Sub&gt;1-4&lt;/Sub&gt;-alkyl;</p><p>A glycoconjugate having the general formula: &lt;Chemistry id="chema03" num="0003"&gt;&lt;Image id="ia03" he="4" wi="46" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein n is an integer of from 1-10, inclusive, m is an integer of from 2-20, inclusive, R is selected from the group consisting of alkyl having at most 25 carbon atoms and aryl and R" constitutes a carrier;</p><p>A bi-dentate 0-glycoside having the general formula: &lt;Chemistry id="chema04" num="0004"&gt;&lt;Image id="ia04" he="4" wi="46" file="IMGA0004.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein m, n and R have the above meaning; and processes for their preparation.</p>
申请公布号 EP0098252(A2) 申请公布日期 1984.01.11
申请号 EP19830850176 申请日期 1983.06.21
申请人 SVENSKA SOCKERFABRIKS AB 发明人 DAHMEN, JAN;FREJD, TORBJORN;MAGNUSSON, GORAN;NOORI, GHAZI
分类号 G01N33/53;A61K39/385;C07H3/06;C07H15/04 主分类号 G01N33/53
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