发明名称 |
CYCLOHEPTENE DERIVATIVES |
摘要 |
<p>RAN 4016/17 The novel cycloheptene derivatives of the general formula I wherein R1 signifies lower alkyl, the dotted line signifies an optional bond and n signifies the number 1, 2 or 3, and either R2 signifies hydrogen or lower alkyl and R3 signifies lower alkyl or R2 and R3 together with the nitrogen atom signify a 5- or 6-membered heterocycle, and their pharmaceutically acceptable acid addition salts have valuable histamine-H1 antagonistic properties and are suitable for the control or prevention of allergic reactions such as urticaria, hay fever, anaphylaxis and over-sensitivity to medicaments. These compounds can be manufactured according to various processes starting from partly novel starting materials and can be brought into galenical administration forms.</p> |
申请公布号 |
CA1160219(A) |
申请公布日期 |
1984.01.10 |
申请号 |
CA19810393178 |
申请日期 |
1981.12.23 |
申请人 |
HOFFMANN-LA ROCHE LIMITED |
发明人 |
ASCHWANDEN, WERNER;BRANCA, QUIRICO;KYBURZ, EMILIO;PFISTER, RUDOLF |
分类号 |
C07D295/02;A61K31/00;A61P37/08;C07C1/00;C07C13/547;C07C67/00;C07C209/00;C07C209/04;C07C209/08;C07C209/22;C07C211/32;C07D295/03;(IPC1-7):C07C87/459 |
主分类号 |
C07D295/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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