| 发明名称 |
SUBSTITUTED 3,4-DIAMINO-1,2,5-THIADIAZOLES HAVING HISTAMINE H2-RECEPTOR ANTAGONIST ACTIVITY |
| 摘要 |
Histamine H2-receptor antagonists of the formula <IMAGE> wherein A, m, Z, n and R<1> are as defined herein, and their nontoxic pharmaceutically acceptable salts, hydrates and solvates are novel anti-ulcer agents which are prepared by ring closure of a substituted ethanediimidamide of the formula <IMAGE> |
| 申请公布号 |
ZA8302154(B) |
申请公布日期 |
1983.12.28 |
| 申请号 |
ZA19830002154 |
申请日期 |
1983.03.25 |
| 申请人 |
BRISTOL-MYERS CO |
发明人 |
CRENSHAW RONNIE RAY;ALGIERI ALDO ANTONIO |
| 分类号 |
A61K31/155;A61K31/41;A61K31/433;A61K31/44;A61K31/4402;A61K31/4418;A61K31/445;A61K31/495;A61P1/00;A61P1/04;A61P43/00;C07C67/00;C07C239/00;C07C257/14;C07C313/00;C07C319/20;C07C321/20;C07C321/28;C07C323/41;C07D207/06;C07D211/14;C07D211/70;C07D213/36;C07D213/64;C07D239/26;C07D279/12;C07D285/06;C07D285/10;C07D295/08;C07D295/12;C07D307/52;C07D333/20;C07D417/12;C07D417/14 |
主分类号 |
A61K31/155 |
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