摘要 |
A compound of the formula: <IMAGE> wherein R1 is (A) a group of the formula, <IMAGE> wherein R4 is H, a halogen or trifluoromethyl group, or (B) a group of the formula, <IMAGE> wherein n is 0 or an integer of 1 to 3; R5 is H or an alkyl group of 1 to 6 carbon atoms; respective R6 and R7 are an alkyl group of 1 to 6 carbon atoms, an alkenyl group of 2 to 6 carbon atoms, a cycloalkyl group of 3 to 7 carbon atoms, or a cycloalkenyl group of 5 to 7 carbon atoms; R6 and R7 may be combined with the neighboring carbon atom to represent a cycloalkyl group of 3 to 7 carbon atoms; a cycloalkenyl group of 5 to 7 carbon atoms, a bicycloalkyl group of 7 to 10 carbon atoms, or a bicycloalkenyl group of 7 to 10 carbon atoms; R2 is an alkyl group of 1 to 6 carbon atoms; and R3 is H, an alkyl group of 1 to 6 carbon atoms or an aralkyl group, or a pharmaceutically acceptable salt thereof. The compound has hypoglycemic, glucose tolerance improving and insulin sensitivity potentiating activities. |