| 摘要 |
<p>L-leucine is prepared by cultivation of an analogue-resistant mutant of Arthrobacter citreus in an aqueous nutrient medium under aerobic conditions. The cultivation is preferably carried out at about 30 DEG C. and at a pH of 5 to 0.8. L-leucine is recovered from the fermentation broth. In a preferred embodiment the mutant is further mutated, and the second mutant is similarly fermented to prepare L-leucine.</p> |
