| 摘要 |
<p>Disclosed herein is a secretin-containing composition which comprises, as an intimate mixture or a combination of separate units, secretin and one or more additives selected from the group consisting of lecithin, ethylene oxide-propylene oxide copolymers, hydroxypropylcellulose, methylcellulose, polyoxyethylene hydrogenated castor oil, polyethylene glycol sorbitan oleate and methylcyclodextrin. Also disclosed is a method to prevent the adsorption of secretin by incorporating one or more of the above additives in a solution of secretin. Use of such additives has been found to be very effective, even at very low concentration levels, in preventing secretin from being adsorbed on the walls of plastic- or glass-made syringe barrels infusion bottles or dripping guide tubes, thereby permitting administration of secretin at accurate dosage levels.</p> |
