| 摘要 |
Compounds of formula I <IMAGE> wherein a) R1 represents a group of formula <IMAGE> wherein R5 and R6 represent independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy, s stands for 3, 4 or 5 and x represents oxygen, sulphur, -CH2-, OCH2-, -SCH2-, or -N(R7)- (R7=hydrogen or lower alkyl) and R2 represents hydrogen or lower alkyl or R1 and R2 together with the adjacent carbon atom represent a group of formula <IMAGE> wherein p is 1, 2 or 3, R3 and R4 represent independently hydrogen or lower alkyl and R8 represents halogen, acetal or thioacetal, each optionally lower alkyl, substituted halogen alkenyl, halogen cycloalkyl, lower alkylcycloalkyl, or alkyl which is substituted by lower alkoxy, lower alkylthio, lower halogenalkyl, acetal, thioacetal, cyano, formyl or hydroxy whereby hydroxy if present is other than ??? to the triple bond or b) R3 and R4 together form a -(CH2)u- group wherein u stands for 3, 4 or 5, R1 represents a group of formula IIa, IIb or IIc, R2 represents hydrogen or lower alkyl and R5 to R8 have the meanings given above, in the free base or in acid addition salt form. The compounds possess anti-mycotic activity. |
