Processes for preparing therapeutically active dihydropyridines and intermediates for the processes.

摘要

New compounds useful as therapeutical agents and useful as intermediates for the preparation of other therapeutically active di-hydropyridines, which new compounds are of the formula <CHEM> wherein R<1> in one or two (the same or different) substituents on the phenyl ring selected from the group consisting of NO2, Cl and lower alkyl; R is -CH3, -CHO or <CHEM> wherein R<1><1> and R<1><2> are same or different, straight or optionally branched lower alkyl or both together are part of 5-7 membered ring, provided that when one of R is -CH3 the other is -CHO or <CHEM> wherein R<1><1> and R<1><2> have the meaning given above; processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and new processes using said compounds as intermediates for the preparation of therapeutically active dihydropyridines.