发明名称 ENANTIOMERS OF HEXAHYDRA-1H-INDOLO 3,2,1-DE - 1,5- NAPHTHYRIDINE
摘要 Enantiomers of the title compound of the formula: <IMAGE> which have hitherto not been characterised specifically, are isolated from their mixtures by preparing addition salts with an enantiomer of a chiral acid. The diastereoisomers obtained are separated by fractional crystallisation and then converted back to the form of the base or of a pharmaceutically acceptable acid addition salt. The enantiomers of the above named compound are useful in therapy as they possess an antianoxic activity.
申请公布号 AU1461683(A) 申请公布日期 1983.11.24
申请号 AU19830014616 申请日期 1983.05.17
申请人 SYNTHELABO 发明人 ALEXANDER WICK;JEAN BERTIN;JONATHAN FROST
分类号 A61K31/435;A61P9/00;C07D471/16 主分类号 A61K31/435
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