发明名称 |
ENANTIOMERS OF HEXAHYDRA-1H-INDOLO 3,2,1-DE - 1,5- NAPHTHYRIDINE |
摘要 |
Enantiomers of the title compound of the formula: <IMAGE> which have hitherto not been characterised specifically, are isolated from their mixtures by preparing addition salts with an enantiomer of a chiral acid. The diastereoisomers obtained are separated by fractional crystallisation and then converted back to the form of the base or of a pharmaceutically acceptable acid addition salt. The enantiomers of the above named compound are useful in therapy as they possess an antianoxic activity. |
申请公布号 |
AU1461683(A) |
申请公布日期 |
1983.11.24 |
申请号 |
AU19830014616 |
申请日期 |
1983.05.17 |
申请人 |
SYNTHELABO |
发明人 |
ALEXANDER WICK;JEAN BERTIN;JONATHAN FROST |
分类号 |
A61K31/435;A61P9/00;C07D471/16 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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