发明名称 |
SULFUR-CONTAINING PHOSPHONIC ACIDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS OR ESTERS AND PHARMACEUTICAL COMPOSITION BASED ON SAID |
摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to sulfur-containing phosphonic acids of the formula (I) <EMI ID=0.422 HE=21 WI=51 TI=CHI> where R is a group -PO<SB>3</SB>H<SB>2</SB> or P(O)(OH)R where R - alkyl; R - hydrogen atom, C<SB>1-8</SB>-alkyl possibly substituted with phenyl, phenyl or two adjacent carbon atoms that in common with R form cyclopentane or cyclohexane; R is C<SB>1-8</SB>-alkyl or phenyl; R - H or OH; n = 1-6, or their pharmaceutically acceptable salts or esters that can be used for prophylaxis and treatment of patients with disorders of calcium and phosporus metabolism. EFFECT: valuable pharmacological properties of compounds. 6 cl, 2 tbl, 26 ex
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申请公布号 |
RU2136691(C1) |
申请公布日期 |
1999.09.10 |
申请号 |
RU19940046117 |
申请日期 |
1993.05.26 |
申请人 |
DZE PROKTER EHND GEHMBL FARMAS'JUTIKALZ, INK. |
发明人 |
SJUZN MEHRI KAAS;FRANK KHEHLLOK IBITINO;MARION DEHVID FREHNSIZ |
分类号 |
A61K31/66;A61K31/662;A61K31/663;A61K31/665;A61K31/67;A61K31/675;A61P3/00;A61P3/14;A61P19/08;A61P19/10;A61P29/00;A61P43/00;C07F;C07F9/30;C07F9/38;C07F9/40;C07F9/547;C07F9/553;C07F9/572;C07F9/576;C07F9/58;C07F9/59;C07F9/6506;C07F9/6512;C07F9/655;C07F9/6553;C07F9/6561;(IPC1-7):C07F9/30 |
主分类号 |
A61K31/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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