| 发明名称 |
Methods of producing HBsAg |
| 摘要 |
Hepatitis B surface antigen (HBsAg) is produced in vitro in high titer and purity from tissue cultures of cells that shed HBsAg. The cells are grown on hollow fiber capillary units having a molecular weight cut-off of about 10,000.
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| 申请公布号 |
US4416986(A) |
申请公布日期 |
1983.11.22 |
| 申请号 |
US19810225555 |
申请日期 |
1981.01.16 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
MARKUS, HENRY Z.;MCALEER, WILLIAM J. |
| 分类号 |
A61K39/29;C07K14/02;C12N5/02;C12P1/00;C12P21/00;(IPC1-7):C12N5/00 |
主分类号 |
A61K39/29 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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