CYCLOHEPTINDOLOL DERIVATIVES AND THEIR ACID-ADDITION SALTS, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITION CONTAINING THEM

摘要

Novel trans cyclohept[c,d]indolols of the formula I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and optionally substituted aralkyl of 7 to 12 carbon atoms and R1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms and optionally substituted aralkyl of 7 to 12 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having hypotensive and antihypertensive activity and a process for their preparation.