发明名称 |
Preparation of 6-alpha-bromo- and/or 6,6-dibromo-penicillanic acid 1,1-dioxides. |
摘要 |
<p>Preparation of 6 alpha-bromo- and/or 6,6-dibromo-penicillanic acid 1,1-dioxides by diazotising a 6 bêta-amino-penicillanic acid, 1,1-dioxide and subsequently brominating the diazotised compounds. The bromo-compounds prepared according to the invention are valuable intermediates because they can be debrominated to yield penicillanic acid 1,1-dioxide and derivatives thereof. The preparation of 6-diazo-penicillanic aicd 1,1-dioxide and derivatives thereof is also disclosed as well as these new compounds as such.</p> |
申请公布号 |
EP0093465(A2) |
申请公布日期 |
1983.11.09 |
申请号 |
EP19830200541 |
申请日期 |
1983.04.15 |
申请人 |
GIST - BROCADES N.V. |
发明人 |
HENNIGER, PETER WOLFGANG;VAN DER DRIFT, JOHANNES KAREL |
分类号 |
C07D499/87;A61K31/43;A61P31/04;C07D499/00;C07D499/10;C07D499/21;C07D499/86;C07D499/897;C12N9/99;(IPC1-7):07D499/00;07D499/04 |
主分类号 |
C07D499/87 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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