PROCESS FOR PRODUCING BACTERIAL CELLS HAVING A HIGH CONTENT OF ACETATE KINASE

摘要

A process is described for cultivating thermophilic bacteria of the genus Bacillus having the ability to produce acetate kinase, wherein said cultivation is carried out continuously at a dilution rate (D) in the range from about 0.9 .mu.max to 1.0 .mu.max, wherein D is the dilution rate (1/hr), and .mu.max is the maximum specific growth rate (1/hr), to thereby produce bacterial cells having a high content of acetate kinase. The bacterial cells cultivated and harvested by this process have a higher content of acetate kinase per gram of dry cells than bacterial cells obtained by a batch process, and the quantity of cells produced is also high.