| 摘要 |
A peptide of formula (I): X-A-B-C-Trp-D-Y wherein X represents hydrogen, or a terminal nitrogn protecting group selecting from the group consisting of the acyl, aromatic oxycarbonyl, alkyl, aralkyl and aliphatic oxycarbonyl; A represent a valence bond or a L- alpha -amino acid residue; B represent a L- alpha -imino acid residue or a L- alpha -amino acid; C represent a L- alpha -imino acid residue or a neutral L- alpha -amino acid residue; D represents a valence bond or a L- alpha -amino acid residue; and Y represents hydroxy, an amino group or a group of the formula OR, NHR, NR2 or NH-NH-R', wherein R represents a straight chain, branched chain or cyclic (including fused or bridged ring) alkyl group having up to 11 carbon atoms, optionally being substituted; a phenyl group or an aralkyl group having from 7 to 9 carbon atoms; and R' represents hydrogen, any of the groups which R may represent; a straight chain, branched chain or cyclic aliphatic acyl group having from 1 to 11 carbon atoms, optionally substituted by hydroxy, an amino group or a halogen atom; an aromatic acyl group, optionally substituted by hydroxy, amino, or a halogen atom; a straight chain, branched chain or cyclic aliphatic oxycarbonyl group having from 3 to 11 carbon atoms, or an aromatic oxycarbonyl group. |
