发明名称 |
GENE THERAPY FOR SPINAL CORD DISORDERS. |
摘要 |
<p>This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention provides a method to deliver a transgene to a subject's spinal cord by administering a recombinant neurotropic viral vector containing the transgene. The viral vector delivers the transgene to a region of the deep cerebellar nuclei region of the brain. Also provided are compositions and methods to deliver a transgene to a subject's spinal cord by administering a recombinant neurotropic viral vector containing the transgene to the motor cortex region of the subject's brain.</p> |
申请公布号 |
MX2007013734(A) |
申请公布日期 |
2008.03.14 |
申请号 |
MX20070013734 |
申请日期 |
2006.05.02 |
申请人 |
GENZYME CORPORATION. |
发明人 |
DODGE, JAMES;SHIHABUDDIN, LAMYA;PASSINI, MARCO;CHENG, SENG |
分类号 |
A61K48/00;C12N15/86 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|