ANTAGONISM OF CENTRAL NERVOUS SYSTEM DRUGS BY THE ADMINISTRATION OF 4-AMINOPYRIDINE ALONE OR IN COMBINATION WITH OTHER DRUGS

摘要

The use of 4-aminopyridine and congeners or derivatives thereof to antagonize drugs which act at or upon central nervous system receptors, especially dopamine receptors, such as butyrophenones and congeners or derivatives thereof. 4-aminopyridine is used above or in combination with other drugs such as naloxone hydrochloride or yohimbine hydrochloride. The use of 4-aminopyridine overcomes the problems of drug overdoses of drugs which act at or upon central nervous system receptors, especially dopamine receptors by reversing the effects of toxic amounts or toxic dosages.