摘要 |
Compounds of formula (I): <CHEM> wherein R<1> is halogen, alkyl or alkoxy; R<2> is hydrogen, halogen, alkyl or alkoxy; R<3> is an optionally substituted, saturated, unsaturated or aromatic, carbo- or hetero-, mono- or bi-cyclic group; R<4> is hydrogen or alkyl, -@@ (CH2)n - R<3> is located meta or para to the imidazolinylamino group; one of R<5> and R<6> is hydrogen and the other is hydrogen, alkyl or acyl; and N is 0, 1, 2 or 3, or an acid addition salt thereof, have antidiarrhoeal activity. |