摘要 |
<p>Phospholipid compositions are provided which are useful in the treatment and prophylaxis of gastro-intestinal ulcer disease. Methods of treatment involve peroral administration of anti-ulcer effective amounts of phospholipid compositions. The amounts generally are sufficient to coat a mucosal surface of an ulcer prone area and effective to restore a defective mucosal barrier. The phospholipid surfactants of this invention include cephalins, lecithins, sphingomyelins, inositols and mixtures thereof. Particular types of phospholipid compounds include phosphatidyl cholines, phosphatidyl ethanolamines, phosphatidyl inositols, phosphatidyl glycerols, phosphatidyl serines, sphingomyelins and mixtures thereof.</p> |