The invention provides methods of identifying and making compounds that inhibit the interaction between MUC1 and galectin-3. Also embraced by the invention are in vivo and in vitro methods of inhibiting such an interaction and of inhibiting the expression of galectin-3 by a cell.
申请公布号
WO2008073817(A3)
申请公布日期
2008.09.25
申请号
WO2007US86760
申请日期
2007.12.07
申请人
DANA-FARBER CANCER INSTITUTE, INC.;KUFE, DONALD, W.