LAYOUT METHOD FOR PROTEIN-PROTEIN INTERACTION NETWORKS BASED ON SEED PROTEIN

摘要

A method for visualizing a protein interworking network around seed protein is provided to express the huge protein interworking network with a stable graph and visualize the protein interworking network at high speed by performing mergence centering on a highly physically related node over a plurality of stages, and performing expansion and FDP(Force-Directed Placement) to the final mergence graph. A node list of each sub-graph forming an protein interaction network is extracted and is arranged according to a node adjacency level(220). Seed protein is selected among the arranged node list according to node priority and mergence relation with other nodes(230). A merged node is generated by merging the adjacent nodes around the selected seed protein(240). An initial position of the merged node is selected and the merged node is located on a division point around the seed protein(260).