| 发明名称 |
Ergoline derivatives, process for producing the ergoline derivatives and pharmaceutical compositions containing them. |
| 摘要 |
<p>There are provided ergoline derivatives of the formula (I)
<Chemistry id="chema01" num="0001"><Image id="ia01" he="48" wi="73" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R, represents a hydrogen atom or a methyl group, R<Sub>2</Sub> represents a hydrogen or halogen atom or a methyl group, R<Sub>3</Sub> represents a hydrogen atom or a methoxy group, R<Sub>4</Sub> represents a hydrocarbon group having from 1 to 4 carbon atoms; each of X and W independently represents a hydrogen atom, a methyl group, a chlorine atom or a methoxy group, and n is 0, 1 or 2.</p><p>A method for their preparation is also provided. The compounds have strong anti-prolactin activity.</p> |
| 申请公布号 |
EP0091652(A1) |
申请公布日期 |
1983.10.19 |
| 申请号 |
EP19830103352 |
申请日期 |
1983.04.06 |
| 申请人 |
FARMITALIA CARLO ERBA S.P.A. |
发明人 |
BERNARDI, LUIGI;BRAMBILLA, ENZO;CHIODINI, LAURA;DI SALLE, ENRICO;RUGGIERI, DANIELA;SAPINI, OSVALDO;TEMPERILLI, ALDEMIO |
| 分类号 |
A61K31/435;A61P13/02;A61P15/00;A61P25/00;A61P43/00;C07D457/02;C07D457/06;(IPC1-7):07D457/06;61K31/48;07D457/02 |
主分类号 |
A61K31/435 |
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