发明名称 ANTIARRHYTHMIC TETRAHYDRONAPHTHALENE DERIVATIVES
摘要 Compounds are provided having the structure <CHEM> wherein R<1> and R<2> may be the same or different and are hydrogen, lower alkyl, lower alkenyl, or hydroxy-lower alkyl, or R<1> and R<2>together with the nitrogen atom to which they are attached also form a heterocyclic radical which may contain another heteroatom, namely nitrogen, oxygen or sulfur; R<3> and R<4> may be the same or different and are hydrogen or lower alkyl. These compounds are useful in the treatment of arrhythmia. In addition novel intermediates are provided having the structure <CHEM> wherein R is hydrogen, benzyl or <CHEM> These intermediates are also useful in treating acute myocardial infarction.
申请公布号 DE3064775(D1) 申请公布日期 1983.10.13
申请号 DE19803064775 申请日期 1980.11.12
申请人 E.R. SQUIBB & SONS, INC. 发明人 HAUCK, FREDERIC P.;FOX, RITA T.
分类号 C07D295/10;A61K31/16;A61K31/165;A61P9/00;C07C67/00;C07C231/00;C07C235/06;C07C235/20;C07D263/06;C07D295/185;C07D303/24;C07D303/26;C07D317/22;C07D317/70;(IPC1-7):C07C103/34;C07C103/17;C07D295/18;A61K31/39 主分类号 C07D295/10
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