Medicated module with user selection

摘要

A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments are delivered through a single hollow needle (5). The medicated module (4) is user selectable so that it will deliver both the primary (1) and secondary medicaments (2), or only the primary medicament (1). The module (4) also contains a guard (42) that locks after dose delivery.

主权项

1. A drug delivery system to deliver two or more medicaments operable through a single drug dispense interface, comprising
a. a drug delivery device housing; b. a primary reservoir of medicament containing at least one drug agent; c. a dose button operably connected to the primary reservoir of medicament; d. a medicated module attachable to the housing, the medicated module comprising,
a module housing having a proximal end and a distal end, where the proximal end has a connector configured for attachment to the drug delivery device housing;a secondary reservoir in the form of a capsule in the module housing comprising a first medicament;a guard configured to move in an axial direction during application to an injection site and arranged to serve as a needle guard that can reduce the risk of accidental needle sticks;a proximal needle cannula mounted in the proximal end of the module housing and a distal needle cannula mounted in the selector that are configured to pierce septa located on proximal and distal ends of the capsule; anda moveable selector operably connected to the guard such that the selector is moveable to two or more predetermined positions, said positions comprising:
a first position where the guard is prevented from moving axially and the first medicament in the secondary reservoir is not allowed to be dispensed, anda second position where the guard is free to move axially and the first medicament in the secondary reservoir is allowed to be dispense,where a portion of the proximal end of the housing and a portion of the selector define a cavity for holding the capsule, wherein movement of the selector from the first into the second position decreases the cavity volume such that the capsule is pierced at its proximal and distal portions by the proximal and the distal needle cannula; andwherein a single activation of the dose button causes medicament from the primary reservoir and the medicament from the secondary reservoir of said medicated module to be expelled through the drug dispense interface when the selector is set to one of the predetermined positions.