| 摘要 |
<p>A closed system (20) for separately storing and selectively mixing two components (82, 74), such as a drug and a diluent, under sterile conditions. The closed system (20) can incorporate a drug vial (80) of standard construction. A unique junction (76) of the closed system permits a drug vial with a drug therein to be connected in a sterile manner with a compressible chamber (22) having a diluent therein, after the drug and diluent have been separately sterilized. The junction (76) encloses the end portions (78, 104) of access means (44, 90) to each of the receptacles (22, 80), maintaining the end portions in sterile, spaced relation and providing for the selective establishment of a sterile pathway between the drug and diluent for mixing in a closed environment. The compressible chamber (22) is of a unique design including gas-trapping and reservoir compartments (32, 30) in open communication. The compressible chamber (22) is utilized with the junction (76) to provide an efficient, sterile storage and mixing system.</p> |
