发明名称 |
SYNERGISTIC ANTIPHLOGISTIC PHARMACEUTICAL COMPOSITION |
摘要 |
The invention relates to synergistic antiphlogistic pharmaceutical compositions comprising a pyrido [1,2-a]-pyrimidine derivative of the Formula I <IMAGE> (I) wherein R1 and R2 are lower alkyl and R3 stands for lower alkoxycarbonyl or carbamoyl and the dotted line represents an optionally hydrogenated band or a salt or quaternary salt thereof and 1-[p-chloro-benzoly]-2-methyl-5-methoxy-indolyl-3-acetic acid of the Formula II <IMAGE> (II) The advantage of the compositions is that as a result of the synergistic activity of the compound of the Formula I, the antiphlogistic Indomethacin of the Formula II can be administered in a significantly lower doses and consequently the unfavorable side effects of the latter compound are mitigated. |
申请公布号 |
JPS58172315(A) |
申请公布日期 |
1983.10.11 |
申请号 |
JP19830002924 |
申请日期 |
1983.01.13 |
申请人 |
CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT |
发明人 |
MARIANNA POONGORU;GAABORU NACHIYU;GAABORU HORUBUAATA;MAARIA DAABUIDO;SHIYANDOORU BOJIYOOKII;SHIYAANDORU BUIRAAGU;KATARIN MAARUMAROSHI |
分类号 |
A61K31/40;A61K31/505;A61P29/00 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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