发明名称 WATER-SOLUBLE PEPTIDES AFFECTING GONADAL FUNCTION
摘要 <p>WATER-SOLUBLE PEPTIDES AFFECTING GONADAL FUNCTION ¢im-Bzl D-His6!LRF and ¢D-His (im-Bzl), Pro9-NEt! LRF exhibit hydrophillicity comparable to that of LRF and act as superagonists exhibiting potencies, respectively, about 12 and more than 200 times that of LRF. The peptides or their nontoxic salts can be administered by intravenous, subcutaneous, sublingual, oral, intravaginal, intranasal or rectal routes. The peptides can be used to regulate fertility in male and female mammals, including human beings.</p>
申请公布号 CA1154758(A) 申请公布日期 1983.10.04
申请号 CA19800352676 申请日期 1980.05.26
申请人 SALK INSTITUTE FOR BIOLOGICAL STUDIES (THE) 发明人 RIVIER, JEAN E.F.;VALE, WYLIE W., JR.
分类号 A61K38/04;A61K38/00;A61P5/00;A61P15/00;C07K7/23;C07K14/575;(IPC1-7):C07C103/52 主分类号 A61K38/04
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