摘要 |
<p>The present invention provides novel substituted sulfooxy-pyrimi-dinium, -pyridinium, and -triazinium hydroxide inner salts. These compounds are useful for the treatment of hypertension and peripheral vascular disease. They are formed by reacting the corresponding aminopyrimidine, aminotriazine, and aminopyridine N-oxides with a latent sulfate source such as pyridinium-sulfur trioxide complex. triethylamine-sulfur trioxide complex, chlorosulfonic acid or chlorosuluryl chloride.</p> |