Novel hydroxyphenylacetamides having analgesic and anti-irritant activity.

摘要

A compound, or pharmaceutically acceptable salt thereof, having the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="26" wi="52" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R is a linear or branched C<Sub>3</Sub>-C<Sub>11</Sub> alkyl, alkynyl or aralkyl group, a linear or branched C<Sub>3</Sub>-C<Sub>22</Sub> alkenyl group, or an unbranched or branched C<Sub>6</Sub>-C<Sub>11</Sub> cycloalkyl or cycloalkenyl group; and wherein one of R<Sub>1</Sub> and R<Sub>2</Sub> is OH, the other being OH or H. These hydroxyphenylacetamides have analgesic and/or anti-irritant activity when administered either topically or systemically.