发明名称 |
Pentanedioic acid derivatives. |
摘要 |
<p>Derivates of beta -hydroxy- beta -alkylglutaric acid are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit beta -hydroxy- beta -methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.</p> |
申请公布号 |
EP0089674(A1) |
申请公布日期 |
1983.09.28 |
申请号 |
EP19830102809 |
申请日期 |
1983.03.22 |
申请人 |
G.D. SEARLE & CO. |
发明人 |
LOWRIE, HARMAN SMITH;BARAN, JOHN STANISLAUS |
分类号 |
C07C69/675;A61K31/19;A61K31/20;A61K31/215;A61K31/22;A61P3/06;C07C33/20;C07C51/00;C07C57/26;C07C59/01;C07C59/125;C07C59/245;C07C59/29;C07C59/31;C07C67/00;C07C69/708;C07C69/732;C07C69/734;C07F9/54;(IPC1-7):07C59/29;07C59/245;07C59/31;07F9/54;07C69/608;07C33/20;07C69/675;61K31/19;07C57/26 |
主分类号 |
C07C69/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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