PROCESS FOR THE PREPARATION OF HEXAHYDRONAPHTHACENE DERIVATIVES

摘要

Cyclic compounds of the general formula …… wherein one of R<1> and R<2> is hydrogen and the other is hydrogen or hydroxy or R<1> and R<2> taken together are a protected oxo group; R<3> is hydrogen, hydroxy or acyloxy; R<4> is lower alkyl, esterified carboxy or a group of the formula -C(R<5>, R<6>) -CH2-X; R<5> and R<6> taken together are oxo or protected oxo; X is hydrogen, hydroxy, acyloxy or -(CH2)n-OY; Y is hydrogen, alkyl or acyl and n is 1 or 2; with the proviso that one of R<1> and R<2> is hydrogen and the other is hydroxy or R<1> and R<2> taken together are protected oxo when R<3> is acetoxy and R<4> is acetyl;… processes for the preparation thereof and intermediates in these processes.