发明名称 Tricyclic derivatives of 5,6-dihydro-11H-dibenzo(B,E)azepin-6-one having pharmacological avtivity, and method for their preparation.
摘要 <p>A pharmacologically active compound has the general formula &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="34" wi="51" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;in which R is a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; R, and R&lt;Sub&gt;2&lt;/Sub&gt;, which can be different, represent a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an arylalkyl group, or an arylalkoxy group, or can jointly represent an oxygen atom or a CHCOOR,' group where R&lt;Sub&gt;1&lt;/Sub&gt;' is a hydrogen atom or an alkyl group; and R&lt;Sub&gt;3&lt;/Sub&gt; represents a hydrogen or halogen atom or an alkyl, NH&lt;Sub&gt;2&lt;/Sub&gt;, NO&lt;Sub&gt;2&lt;/Sub&gt;, NHCO-alkyl, NHCO-aryl, NHCONH-alkyl or NHCONH-aryl group.</p><p>These compounds act on the central nervous system and have an anti-convulsant sedative activity.</p>
申请公布号 EP0089322(A1) 申请公布日期 1983.09.21
申请号 EP19830830056 申请日期 1983.03.14
申请人 A. MENARINI S.A.S. 发明人 PESTELLINI, VITTORIO;CHELARDONI, MARIO;GIOLITTI, ALESSANDRO;VOLTERRA, GIOVANNA;FURIO, MARTINO;MELI, ALBERTO
分类号 C07D215/38;A61K31/55;A61P25/08;A61P25/20;C07D223/20;(IPC1-7):07D223/20;61K31/55 主分类号 C07D215/38
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