发明名称 |
Process for increasing glycine levels in the brain and spinal cord |
摘要 |
The level of glycine in the brain and in the spinal cord is regulated by administering a neutral amino acid composition to a human wherein increased or decreased brain and spinal cord levels of glycine is effected when the composition contains increased or decreased amounts of threonine or a precursor of L-threonine. The neutral amino acid composition can be administered alone or concomitantly with a drug which either has the undesirable side effect of suppressing glycine-mediated neurotransmission or whose therapeutic efficacy is enhanced by increasing glycinergic neurotransmission.
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申请公布号 |
US4405629(A) |
申请公布日期 |
1983.09.20 |
申请号 |
US19800145644 |
申请日期 |
1980.05.02 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
WURTMAN, RICHARD J. |
分类号 |
A61K31/195;A61K31/405;(IPC1-7):A61K31/19;A61K31/44 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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