| 发明名称 |
6-.beta.-SUBSTITUTED PENICILLANIC ACIDS AS .beta.-LACTAMASE INHIBITORS |
| 摘要 |
<p>6-.beta.-iodo-substituted penicillanic acids and derivatives thereof as useful enhancers of the effectiveness of several .beta.lactam antibiotics against many .beta.-lactamase producing bacteria, and 6-.beta.-iodo-substituted penicillanic acid derivatives wherein the carboxy group is protected by a conventional penicillin carboxy protecting group as useful intermediates leading to said synergistic agents. A process for converting 6,6-diiodo-penicillanic acid derivatives to the corresponding 6-.beta.-iodo-substituted penicillanic acid congeners.</p> |
| 申请公布号 |
CA1154011(A) |
申请公布日期 |
1983.09.20 |
| 申请号 |
CA19800346906 |
申请日期 |
1980.03.04 |
| 申请人 |
PFIZER INC. |
发明人 |
KELLOGG, MICHAEL S.;HAMANAKA, ERNEST S. |
| 分类号 |
A61K31/43;A61K31/545;C07D499/00;C07D499/04;(IPC1-7):C07D499/00 |
主分类号 |
A61K31/43 |
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