发明名称 NOUVEAUX & (N PYRROLYL)-ACIDES ET LEURS SELS ET ESTERS, UTILES COMME MEDICAMENTS ET PROCEDE POUR LA PREPARATION DE TELS COMPOSES.
摘要 <p>A process for the preparation of alpha-(N-pyrrolyl)-derivative acids, the salts and esters thereof, of the formula <IMAGE> in which R, R1, R2, R3 and R4 are hydrogen atoms or substituted or unsubstituted alkyl, aryl, alkylaryl or heterocyclic radicals and R' is a metal cation, an organic base or an organic radical, wherein the corresponding amino ester is reacted with a dialkoxytetrahydrofuran or a derivative thereof. Certain compounds comprised among those corresponding to the above formula, particularly the DL, D and L-alpha-(N-pyrrolyl)-phenylacetic acids and certain esters thereof. Therapeutical compositions containing such compounds as active ingredient and therapeutical applications of said compounds.</p>
申请公布号 BE896769(A1) 申请公布日期 1983.09.16
申请号 BE19830210793 申请日期 1983.05.17
申请人 ANTIBIOTICOS S.A. 发明人
分类号 A61K31/40;A61P7/02;A61P25/04;C07D207/32;C07D207/327;(IPC1-7):07D/;61K/ 主分类号 A61K31/40
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