发明名称 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines
摘要 Novel compounds having vasodilation and hypotensive effects are represented by the formula <IMAGE> (I) where R1 is halogen, nitro, cyano or lower alkoxy; each of R2 and R3 is lower alkyl, lower haloalkyl, lower alkoxyalkyl, aralkyloxyalkyl, aryloxyalkyl, lower alkenoxyalkyl, N,N-di-lower alkylaminoalkyl, N-lower alkyl-N-aralkylaminoalkyl, piperidylalkyl, 4-lower alkyl piperazinylalkyl, norpholinoalkyl or 1-pyrrolidinylalkyl; R4 is lower alkyl; A is lower alkylene; and R5 is hydrogen, lower alkyl, cycloalkyl of 3 to 7 carbon atoms, or aryl unsubstituted or substituted by one or two substituents selected from halogen, nitro, lower alkyl, lower alkoxy, di-lower alkylamino and cyano. Also disclosed are processes for their preparation.
申请公布号 US4404378(A) 申请公布日期 1983.09.13
申请号 US19820366137 申请日期 1982.04.06
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 MIYANO, TETSUJI;SUZUKI, KUNIO;HARADA, NOBUO
分类号 A61K31/4418;A61K31/4422;A61K31/455;A61K31/495;A61K31/54;A61P9/08;A61P9/10;A61P9/12;C07D211/90;(IPC1-7):C07D413/12 主分类号 A61K31/4418
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