发明名称 ERYTHRO-9-(2-ACYLOXY-ALK-3-YL) HYPOXANTHINE DERIVATIVES
摘要 <p>There are prepared compounds of the formula <IMAGE> where R1 is alkyl of 1 to 8 carbon atoms and R2 is the ester group of an unsubstituted monocarboxylic acid, aromatic carboxylic acid, aminocarboxylic acid, unsubstituted dicarboxylic acid, phosphoric acid, or nitric acid or a glycoside or an acetaldehyde acetal. The compounds are immunomodulators, have antiviral activity and antitumor activity and also are enzyme inhibitors. The compounds can also be used to introduce the corresponding alcohol into biological systems, in some cases with enhanced potency.</p>
申请公布号 NZ196295(A) 申请公布日期 1983.09.02
申请号 NZ19810196295 申请日期 1981.02.18
申请人 NEWPORT PHARMACEUTICALS INTERNATIONAL INC;SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH 发明人 SIMON L;GINER SOROLLA A;GUTTAG A
分类号 A61K31/52;A61K31/522;A61K31/70;A61K31/7028;A61P31/12;A61P35/00;A61P37/02;A61P37/04;A61P37/06;C07D473/00;C07D473/30;C07H15/26 主分类号 A61K31/52
代理机构 代理人
主权项
地址