摘要 |
NEW MATERIAL:A compound of formulaI(R<1> is H, formula II; R<2> is H, lower alkyl, formula III, where, when R<1> is H, R<2> is formula III). EXAMPLE:Methyl 3beta-O- beta-D-glucopyranosyl-(1 2)-alpha-L-arabinopyranosyl -pomolate. USE:A preventive and curing agent for thrombosis, or a lipid metabolism improver. PREPARATION:For example, SHINA-HIIRAGI (Ilex Cornuta in Aquifoliaceae) is extracted with a polar solvent such as methanol, the extract is concentrated under reduced pressure to give the primary extract. The extract is treated with activated carbon, silica gel, or ion exchange resin to utilize the difference in adsorbability and affinity to isolate compounds of formula IV and V. When necessary, the compound of formula IV is esterified to give the compound of formulaIwhere R<2> is lower alkyl. |