发明名称 MEDICINAL COMPOSITION FOR THE TREATMENT OF CERTAIN NEUROVIROSES
摘要 The pharmaceutical composition as per the present invention, formulated as injectable solution, is composed of the calcium and sodium salt of the ethylenediaminotetracetic acid, associated with calcium gluconate as a source of Ca<2+> ions and aminoacid, preferably cysteine, or a tripeptide-glutathion, the association ratio for the three ingredients being 8...12; 0.3,,,1; 0.05...0.2. This drug has a specific curative action in the treatment of certain neuroviroses: Herpes Zoster, herpes, encephalomyelitis, multiple sclerosis, polyradiculoneuritis, cranial nerves paralysis as well as certain types of dementia porphyriam Wilson's disease. The mechanism of action is based on the antivirotic action of chelators manifested by the modification of the equilibrium of metal ions involved in viruses multiplication and by the restoring of certain lesions of the cell membrane and, implicitly, of certain neuronal activities, through fluctuations of the extracellular Ca<2+> concentration. This drug is also effective in the autoaggressive processes, as it has a strong anti-inflammatory and trophic action. The calcium and sodium salt of the ethylenediaminotetracetric acid associated with calcium gluconate and cysteine is not toxic, if the prescribed dosage is observed.
申请公布号 WO8302893(A1) 申请公布日期 1983.09.01
申请号 WO1982RO00007 申请日期 1982.12.08
申请人 CENTRALA INDUSTRIALA DE MEDICAMENTE, COSMETICE C 发明人 DINU, ROMULUS, CONSTANTIN;DINU, ILEANA, DANA
分类号 A61K31/19;A61K9/08;A61K31/191;A61K31/195;A61K31/198;A61K38/00;A61K38/06;A61P17/00;A61P25/00;A61P29/00;A61P31/12;(IPC1-7):61K31/195;61K9/08;61K37/02;61K31/70 主分类号 A61K31/19
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