发明名称 NOVEL INTERMEDIATES AND PROCESS FOR PREPARING(S)-3-ACYLAMINO-4-SUBSTITUTED-2-AZETIDINONES
摘要 Compounds having the formula <CHEM> can be prepared by reacting a compound having the formula <CHEM> with a Grignard reagent having the formula R3-Mg-X1, wherein R1 is phenylacetyl or phenoxyacetyl; R2 is not readily enolyzable alkyl group, aryl or norbornyl; R3 is alkyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl, 2-phenylethynyl, aryl or arylalkyl; X1 is bromine or chlorine. (3R-cis)-3-Acylamino-4-norbornylsulfonyl-2-azetidinones are novel compounds that form an integral part of this invention.
申请公布号 ZA8207199(B) 申请公布日期 1983.08.31
申请号 ZA19820007199 申请日期 1982.09.30
申请人 SQUIBB & SONS INC 发明人 MUELLER RICHARD HENRY;CIMARUSTI CHRISTOPHER MICHAEL;KISSICK THOMAS PABST
分类号 C07D205/08;C07D205/085;C07D205/095;C07D499/00 主分类号 C07D205/08
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