发明名称 FREMGANGSMAADE TIL FREMSTILLING AF 2-(4-(2-THIAZOLYLOXY)PHENYL)-PROPIONSYRE
摘要 Improved process for the production of 2-[4-(2-thiazolyloxy)phenyl]propionic acid which comprises methylating the isopropyl, sec-butyl, tert-butyl or benzhydryl ester of 2-[4-(2-thiazolyloxy)phenyl]acetic acid with methyl bormide in dimethylformamide at -5 to 5 DEG C in the presence of powdered potassium hydroxide and hydrolyzing the ester group with sodium hydroxide at 0 - 70 DEG C in an aqueous alcohol solution.
申请公布号 DK95283(A) 申请公布日期 1983.08.27
申请号 DK19830000952 申请日期 1983.02.25
申请人 SHIONOGI & CO. LTD. 发明人 HAMADA YOSHINORI;ANDO SATORU
分类号 C07D277/20;C07D277/34 主分类号 C07D277/20
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