发明名称 Antiarrhythmic phenethylpiperidine compounds
摘要 2-Phenethylpiperidines bearing urea, thiourea, and amidine substituents in the ortho-position of the phenethyl moiety have been synthesized and demonstrate useful antiarrhythmic properties. These novel compounds are prepared by reaction of appropriately substituted o-amino-phenethylpiperidines with appropriately substituted phenyl isothiocyanates, phenyl isocyanates, or phenyl imino esters.
申请公布号 US4399286(A) 申请公布日期 1983.08.16
申请号 US19810283710 申请日期 1981.07.16
申请人 MEAD JOHNSON & COMPANY 发明人 LAWSON, JOHN E.
分类号 C07D211/28;A61K31/445;A61K31/451;A61P9/06;A61P29/00;C07D211/26;(IPC1-7):C07D211/28 主分类号 C07D211/28
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